Claire Wright

Claire Wright, Ph.D.

claire.wright@chaminade.edu

Wesselkamper Science Center Room 106
Tel (808) 739-8343

3140 Waialae Ave, Honolulu, HI 96816

Assistant Professor in Biology

Joint Appointment: Non-compensated Assistant Professor, Department of Obstetrics and Gynaecology, John A. Burns School of Medicine, University of Hawaii
Dr Wright completed all of her undergraduate and graduate training in the UK and holds degrees in Physiology, Neuroscience and Neuropathology. Her PhD work was completed in collaboration with GalxoSmithKline where she worked in a team to characterize potential new models for Alzhimer’s Disease. Since her move to Hawaii she has focused her research interests in the field of parturition and has held several university and local foundation grants. Her research program at Chaminade is centered on understanding the mechanisms of the integrity of the tissues of pregnancy as she is committed to improving women’s health care and neonatal outcomes here in Hawaii. Dr Wright has taught at Chaminade since 2012. Prior, she was the primary Neuroanatomy teacher at the John A. Burns School of Medicine in Honolulu and published in the field of medical education. Her broad background in several areas of the biological sciences and her teaching experience gives her the expertise to teach a wide range of biology subjects and to mentor students who wish to perform research.

Education

BSc (Hons) Physiology – University of London, UK
MSc Neuroscience – Institute of Psychiatry, University of London, UK
PhD Neuropathology – The Open University, UK
Post-doctoral fellow – Imperial Collage London, UK
Post-doctoral fellow – University of Hawaii, USA

Teaching

Biology

Research Topics

Professional Service

Publications

  1. Kendal C, Everall I, Polkey C, Al-Sarraj S. (1999) Glial cell changes in the white matter in temporal lobe epilepsy. Epilepsy Research (36) 43-51.
  2. Richardson J. C, Kendal C. E, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlet D, Lavender D, Clarke N. J, Barnes J. C, Howarth R, Stewart M. G and Rupniak T. (2003) Ultrastructural and behavioural changes precede amyloid deposition in a transgenic mouse model of Alzheimer’s disease. Neuroscience 122 (1) 213-229.
  3. Mezey S, Doyère V, De Souza I, Harrison E, Cambon K, Kendal C, Davies H, Laroche S, Stewart M. (2004) Long-term synaptic mophometry changes after induction of LTP and LTD in the dentate gyrus of awake rats are not simply mirror phenomena. European Journal of Neuroscience (19) 1-9.
  4. Anderson AA, Kendal C. E, Garcia-Maya M, Kenny AV, Morris-Triggs S, Wu T, Reyonlds R, Hohenester E and Saffell J. S. (2005) A peptide from the first fibronectin domain of NCAM acts as an inverse agonist and stimulates FGF receptor activation, neurite outgrowth and survival. Journal of Neurochemistry 95(2) 570-83.
  5. Garcia-Maya M, Anderson A. A, Kendal C. E, Kenny A. V, Edwards-Ingram C, Holladay A and Saffell J. S. (2006) Ligand concentration is a driver of divergent signalling and pleiotrophic cellular responses to FGF. J Cell Physiology 206(2):386-93.
  6. Kendal C. E, and Bryant-Greenwood G. D. (2007) Pre-B-cell colony-enhancing factor (PBEF/Visfatin) gene expression is regulated by NF-kB and AP-1 in human amniotic epithelial cells. Placenta 28(4) 305-314.
  7. Kendal-Wright C. E (2007) Stretching, mechanotransduction and proinflammatory cytokines in the fetal membranes. Reproductive Sciences 14 (8)supp 35-41.
  8. Kendal-Wright C. E, Hubbard D and Bryant-Greenwood G. D. (2008) Chronic stretching of amniotic epithelial cells increases Pre-B cell colony-enhancing factor (PBEF/Visfatin) expression and protects them from apoptosis. Placenta 29(3) 255-65.
  9. Mazaki-Tovis, Romero R, Kusanovic J.P, Erez O, Gotsch F, Mittal P, Than N, Nhan-Chang C. L, Hamill N, Vaisbuch E, Chaiworapongsa T, Edwin S, Nien J. K, Gomes R, Espinoza J, Hassan S. S, Kendal-Wright C. E and Bryant-Greenwood G. (2008) Visfatin/Pre-B Cell Colony-Enhancing Factor in Amniotic: An Association with Subclinical Intrauterine Infection in Preterm Parturition. Journal of Perinatal Medicine 36:485-496.
  10. Kendal-Wright C. E, Hubbard D, Gowin-Brown J and Bryant-Greenwood G. Stretch and inflammation-induced Pre-B cell colony-enhancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells. Placenta (2010) 31(8):665-74.
  11. Kendal-Wright C.E, and Kasuya R. Team based learning: A natural addition to the JABSOM curriculum. Hawaii Medical Journal (2010) 69(10):247-8.
  12. Astern J.M, Collier A.C and Kendal-Wright C.E. Pre-B Cell Colony Enhancing Factor (PBEF/NAMPT/Visfatin) and Vascular Endothelial Growth Factor (VEGF) cooperate to increase the permeability of the human placental amnion. Placenta (2012) Nov 12 Epub ahead of print.